Palbociclib for breast cancer is taken 21 days out of 28. Here is what one cycle of 21 tablets costs in seven places, from official price lists.
Researched with AI assistance; every figure is checked against the primary source cited on this page before publishing. How we work →
Ibrance (palbociclib) is one 125 mg tablet a day for 21 days followed by 7 days off — a 28-day cycle of 21 tablets (FDA label); lower doses use 100 or 75 mg. European packs hold 21 tablets or capsules, so we compare one cycle. The two US list figures from CMS are for a “30-day supply” and are shown as published. US dollars at European Central Bank reference rates of November 6, 2026. The price types differ — list price, negotiated price, retail price — and are labelled.
IBRANCE / PALBOCICLIB · ONE 28-DAY CYCLE = 21 TABLETS
Price by country, November 2026
US list price: CMS figure for a 30-day supply (2024). No official price in Germany.
| Country | Official price | 30 days in US dollars | What a patient typically pays |
|---|---|---|---|
| 🇺🇸 United States (list, 2024) | $15,741 for a 30-day supply (CMS, 2024) | $15,741 | — |
| 🇺🇸 United States (Medicare, 2027) | $7,871 negotiated price per 30-day supply, from Jan 1, 2027 (CMS); $380.560323 per tablet | $7,992 per cycle | Depends on the Part D plan and coverage phase |
| 🇬🇧 United Kingdom | Ibrance £2,950.00 for 21 tablets, every strength (NHS price, since Jan 18, 2021) | $3,949 | £9.90 per item in England; free in Scotland, Wales and Northern Ireland |
| 🇨🇭 Switzerland | Ibrance CHF 2,162.80 for 21 tablets or capsules, every strength (public price; limitation) | $2,641 | 10% share after the annual deductible |
| 🇫🇷 France | Ibrance 125 mg €1,633.11 for 21 capsules (official price excluding dispensing fee) | $1,823 | Fully reimbursed (100%) |
| 🇦🇹 Austria | Ibrance €2,063.20 for 21 tablets (social-insurance price excl. VAT; effective price may be lower under a price model) | $2,304 | €7.55 prescription fee per pack; for specified uses, with documentation |
| 🇳🇱 Netherlands | Ibrance €1,624.93 for 21 tablets, €77.38 per tablet (average pharmacy price) | $1,814 | Fully reimbursed; counts toward the annual deductible |
| 🇩🇪 Germany | No statutory price ceiling (Festbetrag) for palbociclib; no official price found | — | — |
We compare prices; we do not recommend where to buy medicine. Cancer treatment decisions belong with your oncology team.
The $7,871 is the price Medicare negotiated under the Inflation Reduction Act for a 30-day supply, effective January 1, 2027. CMS’s data file sets $380.560323 per tablet for every strength, so one 21-tablet cycle comes to $7,992 (our calculation). In 2024 about 16,000 people with Medicare Part D used Ibrance, and Part D spent $2.04 billion on it before rebates (CMS).
The Netherlands, France, Austria, Switzerland and the UK publish an official price for a 21-tablet pack — about $1,814 to $3,949 at ECB rates, or 23% to 49% of Medicare’s 2027 price per cycle (our calculation: $1,814 ÷ $7,992 and $3,949 ÷ $7,992). Put the other way, Medicare will pay about twice the UK price and 4.4 times the Dutch price.
CMS states the $15,741 list price and the $7,871 negotiated price for a 30-day supply calculated from 2024 prescription fills; it does not say how many tablets that is for a 21-days-on, 7-days-off drug. We therefore compare Europe per 21-tablet cycle and show Medicare both ways. Pfizer’s US price disclosure page could not be opened from our location.
CMS recorded a US list price of $15,741 for a 30-day supply in 2024; Medicare’s negotiated price from January 1, 2027 is $7,871 (CMS), or $7,992 for one 21-tablet cycle at $380.56 per tablet (our calculation). In Europe, 21 tablets cost €1,624.93 in the Netherlands, €1,633.11 in France (capsules), €2,063.20 in Austria (excl. VAT), CHF 2,162.80 in Switzerland and £2,950.00 in the UK — about $1,814 to $3,949 at ECB rates.
No: the 75, 100 and 125 mg strengths cost the same per tablet in the CMS data file and per pack in the UK, Switzerland, Austria and the Netherlands.
We found none: CMS negotiates only drugs without generic competition, the Swiss list shows only Ibrance, and the Dutch price list shows only Ibrance and parallel imports.
In England each prescription item costs £9.90; in France it is fully reimbursed; in Switzerland insured patients pay a 10% share after the deductible; in Austria a €7.55 prescription fee for the specified uses; in the Netherlands it is fully reimbursed but counts toward the annual deductible. In Medicare, it depends on the Part D plan.
Twenty-one: one tablet a day for 21 days, then 7 days off, for a 28-day cycle (FDA label).
Wellness Vision does not sell medicine, recommend pharmacies or suppliers, or take payments from drug makers. Every price above comes from the official source cited; currency conversions and 30-day figures are our own calculations, shown with their formula. This is a cost comparison, not medical advice.
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