Rifaximin 550 mg has no generic competitor in the US. Here is what 60 tablets — 30 days at the liver dose — cost in six places, from official price lists.
Researched with AI assistance; every figure is checked against the primary source cited on this page before publishing. How we work →
Xifaxan 550 mg (rifaximin) is taken twice a day to reduce the risk of hepatic encephalopathy returning (FDA label) — so 30 days = 60 tablets. For irritable bowel syndrome with diarrhea it is a 14-day course of three tablets a day. European packs hold 56 tablets; we scale to 60 (our calculation: pack price ÷ 56 × 60). France sells rifaximin 550 mg as Tixtar; the UK now lists it under its generic name. US dollars at European Central Bank reference rates of November 6, 2026. The price types differ — list price, negotiated price, retail price — and are labelled.
XIFAXAN / RIFAXIMIN 550 MG · 30 DAYS = 60 TABLETS
Price by country, November 2026
Packs of 56 scaled to 60 tablets (our calculation). US list price: CMS figure for a 30-day supply (2024). No official price in Germany or Austria.
| Country | Official price | 30 days in US dollars | What a patient typically pays |
|---|---|---|---|
| 🇺🇸 United States (list) | $2,696 for a 30-day supply (CMS, 2024) | $2,696 | Eligible commercially insured patients may pay as little as $0 with the maker’s copay card; not for Medicare or Medicaid (maker’s terms) |
| 🇺🇸 United States (Medicare, 2027) | $1,000 negotiated price per 30-day supply, from Jan 1, 2027 (CMS); $20.199934 per 550 mg tablet | $1,000 | Depends on the Part D plan and coverage phase |
| 🇬🇧 United Kingdom | Rifaximin 550 mg £259.23 for 56 tablets (NHS Drug Tariff price, since May 1, 2013) | $372 | £9.90 per item in England; free in Scotland, Wales and Northern Ireland |
| 🇨🇭 Switzerland | Xifaxan CHF 298.95 for 56 tablets (public price; reimbursed with limitations) | $391 | 10% share after the annual deductible |
| 🇫🇷 France | Tixtar €195.45 for 56 tablets (official price excluding dispensing fee) | $234 | 35% of the price unless a complementary insurer covers it (65% reimbursed) |
| 🇳🇱 Netherlands | Xifaxan €296.82 per pack, €5.30 per tablet (average pharmacy price) | $355 | Fully reimbursed; counts toward the annual deductible |
| 🇦🇹 Austria | No 550 mg rifaximin tablet in the reimbursement code (November 2026) | — | — |
| 🇩🇪 Germany | No statutory price ceiling (Festbetrag) for rifaximin; no official price found | — | — |
We compare prices; we do not recommend where to buy medicine. Whether to take, stop or switch a medicine for hepatic encephalopathy or IBS is a decision for your doctor.
The $1,000 is the price Medicare negotiated under the Inflation Reduction Act, effective January 1, 2027. CMS bases it — like the $2,696 list price — on a 30-day supply calculated from 2024 prescription fills. Its data file sets $20.199934 per 550 mg tablet, so 60 tablets, or 30 days at the twice-daily dose, come to $1,212 (our calculation). In 2024 about 105,000 people with Medicare Part D used Xifaxan, and Part D spent $1.16 billion on it before rebates (CMS).
France, the Netherlands, the UK and Switzerland publish an official price for rifaximin 550 mg — about $234 to $391 for 60 tablets at ECB rates, or 9% to 15% of the US list price (our calculation: $234 ÷ $2,696 and $391 ÷ $2,696). Even at Medicare’s 2027 price per tablet, 60 tablets cost about three times the Swiss price (our calculation: $1,212 ÷ $391).
Salix’s copay card lets eligible commercially insured patients pay as little as $0, but it excludes anyone using Medicare, Medicaid or another government program (maker’s terms). France rates the medical benefit of Tixtar as important only for preventing relapses of hepatic encephalopathy after at least two previous episodes (public medicines database), and Switzerland reimburses Xifaxan with limitations.
CMS put the US list price at $2,696 for a 30-day supply in 2024; Medicare’s negotiated price from January 1, 2027 is $1,000 (CMS). In Europe, 56 tablets of rifaximin 550 mg cost £259.23 in the UK, €195.45 in France (Tixtar) and CHF 298.95 in Switzerland, and the Netherlands averages €5.30 per tablet — about $234 to $391 for 60 tablets at ECB rates.
CMS states the $1,000 for a 30-day supply calculated from 2024 prescription fills. Its data file prices each 550 mg tablet at $20.199934; at two tablets a day, 60 tablets come to $1,212 (our calculation).
Not in the US: CMS selects only drugs without generic competition, and Xifaxan was selected for 2027. In the UK the NHS now lists rifaximin 550 mg under its generic name, at the Drug Tariff price of £259.23 for 56 tablets.
In the US, eligible commercially insured patients may pay as little as $0 with Salix’s copay card, which excludes Medicare and Medicaid. In England each prescription item costs £9.90; in Switzerland insured patients pay a 10% share after the deductible; in France 65% is reimbursed; in the Netherlands it is fully reimbursed but counts toward the annual deductible.
Tixtar is the name under which Alfasigma sells rifaximin 550 mg tablets in France (public medicines database). It contains the same active substance as Xifaxan.
Wellness Vision does not sell medicine, recommend pharmacies or suppliers, or take payments from drug makers. Every price above comes from the official source cited; currency conversions and 30-day figures are our own calculations, shown with their formula. This is a cost comparison, not medical advice.
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